[HTML][HTML] The diagnostic and prognostic significance of SCUBE1 levels in Crimean-Congo hemorrhagic fever

A Menteşe, G Yilmaz, A Sümer, M Arslan… - International Journal of …, 2013 - Elsevier
Background The new biochemical marker, signal peptide-CUB-EGF domain-containing
protein 1 (SCUBE1), is secreted and cell surface glycoprotein expressed during early
embryogenesis. The protein is found in platelet and endothelial cells. Crimean-Congo
hemorrhagic fever (CCHF), which is caused by a tick-borne virus belonging to the
Bunyaviridae family, may present with a mild clinical course or may exhibit a severe profile
with potentially fatal hemorrhaging. The aim of this study was to determine the diagnostic …
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